Antidotal treatment of cyanide poisoning involves three strategies Lethal, so clinicians must stabilize the patient’s airway, breathing and circulation first. The treatment of patients poisoned with cyanide includes supportive care and adjunctive antidotal therapy. The confirmatory test for cyanide poisoning and but it is not routinely performed in most hospitals and may not correlate with toxicity therefore it cannot A cutoff point of 8 mmol/L lactate level should be suggested as a diagnostic indicator of cyanide toxicity. Cyanide-poisoned patients have an elevatedīlood lactate concentration.

Symptoms theoretically those are cherry-red skin and odor of bitter almond from the victims’ breath. Cyanide toxicity expected to have two characteristic Central nervous system and cardiovascular system dysfunction are most prominent also there are nonspecific sings suchĪs nausea, vomiting, headache, dizziness, confusion, coma, seizures, dilated pupils, and abnormal vital signs. The clinical presentation varies with the physicochemical form of cyanide, the dose, route of entry,Ĭo-toxicants delay since exposure. Symptoms than does oral or transdermal ingestions. Intravenous and inhaled cyanide exposures produce more rapid onset of signs and Most common cause of cyanide poisoning is smoke inhalation. It has many natural, industrial and even household sources. Cyanide is a rapidly acting, lethal poison that interfere with mitochondrial oxygen utilization.

Cyanide poisoning antidote mechanism